I love when people quote Shakespeare and have no idea what they're talking about. The actual speech begins:
If music be the food of love, play on;
Give me excess of it, that, surfeiting,
The appetite may sicken, and so die.
Duke Orsino is suggesting that if he listens to enough music, it will be like eating too much food, and help kill his love and desire for Lady Olivia. Get it? It's just like when you read a lot of Mary Worth and you lose your appetite.
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